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Home - Products - Endocrinology/Hormones - 5-HT Receptor - RU 24969 hemisuccinate

RU 24969 hemisuccinate

CAS No. 66611-27-6

RU 24969 hemisuccinate( —— )

Catalog No. M27644 CAS No. 66611-27-6

RU 24969 is a selective agonist at the 5-HT1A and 5-HT1B receptors.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    RU 24969 hemisuccinate
  • Note
    Research use only, not for human use.
  • Brief Description
    RU 24969 is a selective agonist at the 5-HT1A and 5-HT1B receptors.
  • Description
    RU 24969 is a selective agonist at the 5-HT1A and 5-HT1B receptors.
  • In Vitro
    RU 24969 (10 μM) reduces K+-stimulated release of [3H]-5-HT from ratfrontalcortex slices in vitro.
  • In Vivo
    RU 24969 (0.03-3.0 mg/kg; s.c.) dose-dependently decreases water consumption in water deprived rats.RU 24969 (0.3-3.0 mg/kg; s.c.) dose-dependently increases forward locomotion. Animal Model:Male Sprague-Dawley rats Dosage:0.03, 0.3, 1.0, 3.0 mg/kg Administration:A single s.c.Result:Decreased water consumption significantly at dose of 0.3, 1.0, and 3.0 mg/kg.
  • Synonyms
    ——
  • Pathway
    Endocrinology/Hormones
  • Target
    5-HT Receptor
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    66611-27-6
  • Formula Weight
    574.67
  • Molecular Formula
    C32H38N4O6
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    c1(ccc2c(c1)c(c[nH]2)C1=CCNCC1)OC.C(=O)(CCC(=O)O)O.c1(ccc2c(c1)c(c[nH]2)C1=CCNCC1)OC
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Hirose K, et al. Boron neutron capture therapy using cyclotron-based epithermal neutron source and borofalan (10B) for recurrent or locally advanced head and neck cancer (JHN002): An open-label phase II trial. Radiother Oncol. 2021 Feb;155:182-187.
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